While on one of its first test flights in 2374 the Prometheus was hijacked by Romulans whokilled the rest of its crew. While escaping Federation space the Prometheus was interceptedby a Nebula-class, Akira-class, and two Defiant-class vessels. Control of the ship wasregained by it's EMH and the EMH doctor from the USS Voyager.
Named after the Greek Titan that gave mankind fire.
"Message in a Bottle" - VOY